We are in tireless pursuit of breakthroughs that change patients' lives. We create innovations daily to make the world a healthier place. It was Charles Pfizer's original vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies deliver better results, are more innovative, draw and keep the best people, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and reflects our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and represents the value we aim to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We fulfill our purpose by finding the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.