We're in constant pursuit of breakthroughs that change patients' lives. We create innovations each day to make the world a healthier place. It was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, draw and keep the best professionals, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for expanding our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and embodies the value we aim to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.