We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a better place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, recruit and maintain the best professionals, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and shows our passion for growing our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and reflects the value we aim to bring to patients and society. Our purpose makes certain that patients remain at the heart of all we do. We embody our purpose by finding the best science in the world, partnering with others in the healthcare system to improve access to our medicines, using digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.